Progressive retinal atrophy

Progressive retinal atrophy (PRA) is a group of genetic diseases seen in certain breeds of dogs and, some times on cats. Similar to retinitis pigmentosa in humans, it is characterized by the  degeneration of the retina, causing progressive vision loss leading to blindness. The condition in nearly all breeds is inherited as an autosomal recessive trait, with the exception of the Siberian Husky (inherited as an X chromosome linked trait) and the Bullmastiff (inherited as an autosomal dominant trait).[2] There is no treatment.

We are using DNA tested CLEAR father,  so that the puppies will not be affected from this disease.

Commonly affected breeds

Labrador Retriever
Golden Retriever
Border Collie
Collie
Shetland Sheepdog
English Cocker Spaniel
English Springer Spaniel
Chesapeake Bay Retriever
Poodle                                                                                                                                                                                                                                                         Briard – has an especially high frequency.

Diagnosis

For many breeds there are specific genetic tests of blood or buccal mucosa for PRA.[2]
Absent a genetic test, animals of breeds susceptible to PRA can be cleared of the disease only by the passage of time—that is, by living past the age at which PRA symptoms are typically apparent in their breed. Breeds in which the PRA gene is recessive may still be carriers of the gene and pass it on to their offspring, however, even if they lack symptoms, and it is also possible for onset of the disease to be later than expected, making this an imperfect test at best.

 

Source

http://en.wikipedia.org/wiki/Progressive_retinal_atrophy

 

Prevention

Study indicates that this disease will occur if both mother and father of a puppy have the same disorder or carriers.

For example :

Case 1: Mother is carrier of genetic disorder and Father is a Carrier of this Genetic disorder (they them self is not affected)

Chance of puppies: Can be affected, Can be carrier or Can be clear

Case 2: Only one of Mother or Father is affected. Other one is clear

Puppies can be carriers (they themselves are not affected)

We are using DNA tested CLEAR father only so that the puppies will not be affected from this disease.

All our male dogs are DNA tested for Progressive retinal atrophy